A reliable spot test for mucopolysaccharidoses.
نویسندگان
چکیده
From the Department of Ophthalmology, Biochemistry Research Laboratory (The Sir Isaac and Lady Wolfson Ophthalmic Research Laboratories), Hebrew University-Hada.ssah Medical School, Jerusalem, Israel. 1 Present address: Department of Biophysics, Weizmann InstituteofScience,Rehovot,Israel. Nonstandard abbreviations used: MPS, mucopolysaccharides (glycosaminoglycans),mucopolysaccharidoses (with roman numerals); C/O, carbazole/orcinol (ratio of results by these methods); Tris,tris(hydroxymethyl)aminomethane. Received Mar. 24, 1971;acceptedMay 19,1971.
منابع مشابه
The spot test is not a reliable screening procedure for mucopolysaccharidoses.
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OBJECTIVE The first line-screening test for mucopolysaccharidosis is based on measurement of urinary glycosaminoglycans. The most reliable test for measurement of urine glycosaminoglycans is the 1,9-dimethyleneblue colorimetric assay. Biological markers are affected by ethnical factors, for this reason, the World Health Organization recommends that the diagnostic test characteristics should be ...
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ورودعنوان ژورنال:
- Clinical chemistry
دوره 17 9 شماره
صفحات -
تاریخ انتشار 1971